Across TCGA cell cohorts, MACO1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,004 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MACO1-associated genes across cancer lineages are BSDC1, STX12, and FBXO42. Each is linked with MACO1 in more than 14 cancer types. Because this analysis shows association rather than direction, both MACO1-to-partner and partner-to-MACO1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MACO1→partner) and Y-score (partner→MACO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	BSDC1 →	+1.088	+0.860	<.001	<.001	3	15
BLOOD_Myeloma	STX12 →	+1.047	+0.711	<.001	.001	1	15
UPPER_AERODIGESTIVE_TRACT	FBXO42 →	+0.920	+0.866	<.001	<.001	3	13
STOMACH	FAM76A →	+0.817	+0.731	.002	<.001	3	13
LARGE_INTESTINE	DNAJC16 →	+0.847	+0.596	<.001	<.001	3	12
LUNG_SCLC	WDTC1 →	+1.044	+0.974	<.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,004 associations by consensus.

Exploration

MACO1 survival (RNA) · tumor vs normal (RNA) · all MACO1 data types