MACIR

Across TCGA cell cohorts, MACIR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,054 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MACIR-associated GO terms across cancer lineages are Regulation of rRNA processing, Positive regulation of rRNA processing, and DNA synthesis involved in DNA replication. Each is linked with MACIR in more than 8 cancer types. Because this analysis shows association rather than direction, both MACIR-to-partner and partner-to-MACIR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of rRNA processing grouped by MACIR-low versus MACIR-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MACIR→partner) and Y-score (partner→MACIR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of rRNA processing →	+0.079	+0.688	.001	.007	2	9
BLOOD_Lymphoma	Positive regulation of rRNA processing →	+0.103	+1.034	.001	<.001	3	7
BLOOD_Myeloma	DNA synthesis involved in DNA replication →	+0.079	+0.515	<.001	.004	3	7
CNS	Regulation of fibroblast migration →	+0.111	+1.191	<.001	<.001	3	7
OESOPHAGUS	Double-strand break repair via nonhomologous end joining →	+0.059	+1.055	.005	.004	1	9
BLOOD_Myeloma	Regulation of G2/M transition of mitotic cell cycle →	+0.068	+0.702	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,054 associations by consensus.

Regulation of rRNA processing by MACIR expression — LARGE_INTESTINE

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