M1AP

Across TCGA cell cohorts, M1AP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,966 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible M1AP-associated GO terms across cancer lineages are Male meiosis chromosome segregation, Meiotic chromosome separation, and Meiotic DNA double-strand break formation. Each is linked with M1AP in more than 16 cancer types. Because this analysis shows association rather than direction, both M1AP-to-partner and partner-to-M1AP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Male meiosis chromosome segregation grouped by M1AP-low versus M1AP-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (M1AP→partner) and Y-score (partner→M1AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Male meiosis chromosome segregation →	+1.623	+2.573	<.001	<.001	3	17
BLOOD_Leukemia	Meiotic chromosome separation →	-0.294	-1.265	<.001	<.001	3	9
SKIN	Meiotic DNA double-strand break formation →	-1.017	-0.414	<.001	<.001	3	8
BONE	Establishment of protein localization to vacuole →	+0.102	+0.533	<.001	.003	3	6
BLOOD_Leukemia	Endosome transport via multivesicular body sorting pathway →	+0.060	+0.824	<.001	<.001	3	6
BLOOD_Leukemia	Late endosome to vacuole transport →	+0.074	+1.008	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,966 associations by consensus.

Male meiosis chromosome segregation by M1AP expression — OVARY

Explore this box plot interactively →