LZTS2

Across TCGA patient cohorts, LZTS2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,054 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LZTS2-associated genes across cancer lineages are BMPR1A, EIF3A, and TNKS2. Each is linked with LZTS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both LZTS2-to-partner and partner-to-LZTS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LZTS2 versus BMPR1A in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LZTS2→partner) and Y-score (partner→LZTS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BMPR1A →	+0.555	+0.186	<.001	<.001	3	5
UCEC	EIF3A →	+0.729	+0.277	.003	<.001	3	4
COAD	TNKS2 →	+0.452	+0.373	<.001	.001	3	4
LSCC	LY9 →	-0.567	-0.184	.007	.001	3	4
GBM	CAMK4 →	-0.848	-0.225	<.001	.002	3	4
UCEC	EXOSC1 →	+0.533	+0.203	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,054 associations by consensus.

LZTS2 vs BMPR1A — LSCC

Explore this scatter interactively →