LYST-AS1

Across TCGA patient cohorts, LYST-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,313 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LYST-AS1-associated proteins across cancer lineages are LYST, RGS10, and DOCK11. Each is linked with LYST-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LYST-AS1-to-partner and partner-to-LYST-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYST-AS1 versus LYST in UCEC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYST-AS1→partner) and Y-score (partner→LYST-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LYST →	+0.370	+0.960	<.001	<.001	3	5
LUAD	RGS10 →	+0.340	+0.542	.005	.001	3	4
UCEC	DOCK11 →	+0.321	+0.640	.005	.003	3	4
LSCC	LYST_S2105 →	+0.527	+0.643	.001	<.001	3	4
PDAC	FERMT3_S8 →	+0.789	+0.395	<.001	.001	3	3
LSCC	SAMHD1 →	+0.293	+0.362	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,313 associations by consensus.

LYST-AS1 vs LYST — UCEC

Explore this scatter interactively →