LYPD5

Across TCGA patient cohorts, LYPD5 protein abundance is significantly associated with the RNA expression of many other genes, with 1,813 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LYPD5-associated genes across cancer lineages are DUX4L18, RPS4Y2, and FAM155B. Each is linked with LYPD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYPD5-to-partner and partner-to-LYPD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYPD5 versus DUX4L18 in LSCC, with a Pearson correlation of 0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD5→partner) and Y-score (partner→LYPD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DUX4L18 →	+0.070	+2.352	<.001	.003	3	1
LSCC	RPS4Y2 →	+0.389	+2.438	.004	.005	3	1
GBM	FAM155B →	-1.196	-1.323	.005	.008	3	1
GBM	C19orf57 →	-1.113	-1.323	.005	.008	3	1
GBM	THNSL2 →	+1.413	+1.403	.005	.008	3	1
GBM	HTR7P1 →	-0.610	-1.323	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,813 associations by consensus.

LYPD5 vs DUX4L18 — LSCC

Explore this scatter interactively →