LYPD1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LYPD1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,218 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LYPD1-associated genes across cancer lineages are AFAP1L2, DLGAP1, and KCNIP1. Each is linked with LYPD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYPD1-to-partner and partner-to-LYPD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYPD1 versus AFAP1L2 in UCEC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD1→partner) and Y-score (partner→LYPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAFAP1L2 →+1.205+1.117.001<.00132
OVDLGAP1 →+1.040+0.929<.001<.00132
GBMKCNIP1 →+1.677+0.583<.001<.00132
GBMCTXND1 →+0.795+0.499<.001<.00132
UCECLINC00868 →+0.998+0.751.002.00132
OVHSPE1P14 →+0.524+0.742.003<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,218 associations by consensus.

LYPD1 vs AFAP1L2 — UCEC

Per-sample scatter of LYPD1 vs AFAP1L2 in UCEC (Pearson r = 0.46).

Explore this scatter interactively →

Exploration