LY75-CD302

Across TCGA patient cohorts, LY75-CD302 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LY75-CD302-associated genes across cancer lineages are ATRIP, ALKBH5, and TOX4. Each is linked with LY75-CD302 in more than 1 cancer types. Because this analysis shows association rather than direction, both LY75-CD302-to-partner and partner-to-LY75-CD302 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATRIP grouped by LY75-CD302-low versus LY75-CD302-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY75-CD302→partner) and Y-score (partner→LY75-CD302) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATRIP →	+0.220	+3.354	<.001	.007	3	1
UCEC	ALKBH5 →	+0.559	+3.242	.007	.009	3	1
UCEC	TOX4 →	+0.531	+3.201	.006	.009	3	1
UCEC	HARBI1 →	+0.528	+3.201	.002	.009	3	1
UCEC	TM2D3 →	+0.511	+3.210	.004	.009	3	1
UCEC	RNU1-17P →	+0.325	+3.350	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

ATRIP by LY75-CD302 expression — UCEC

Explore this box plot interactively →