LY75-CD302

Across TCGA cell cohorts, LY75-CD302 mutation is significantly associated with the RNA expression of many other genes, with 110 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LY75-CD302-associated genes across cancer lineages are FGF8, EDA, and VRK2. Each is linked with LY75-CD302 in more than 1 cancer types. Because this analysis shows association rather than direction, both LY75-CD302-to-partner and partner-to-LY75-CD302 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGF8 grouped by LY75-CD302-low versus LY75-CD302-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY75-CD302→partner) and Y-score (partner→LY75-CD302) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	FGF8 →	+0.209	+3.399	<.001	.006	3	2
BLOOD_Leukemia	EDA →	+1.397	+3.470	<.001	.004	3	2
SKIN	VRK2 →	+0.441	+3.451	.003	.002	3	2
BLOOD_Myeloma	USP17L15 →	+0.013	+4.807	<.001	.006	3	1
BLOOD_Myeloma	PIGY →	+0.846	+4.807	.001	.006	3	1
URINARY_TRACT	NOBOX →	+0.010	+2.722	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 110 associations by consensus.

FGF8 by LY75-CD302 expression — URINARY_TRACT

Explore this box plot interactively →