LY6H

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LY6H mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LY6H-associated genes across cancer lineages are UNC93A, MUC7, and VN1R2. Each is linked with LY6H in more than 1 cancer types. Because this analysis shows association rather than direction, both LY6H-to-partner and partner-to-LY6H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UNC93A grouped by LY6H-low versus LY6H-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6H→partner) and Y-score (partner→LY6H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaUNC93A →+0.055+4.350<.001.00531
BLOOD_LymphomaMUC7 →+0.025+4.191<.001.00731
BLOOD_LymphomaVN1R2 →+0.009+4.643<.001.00531
BLOOD_LymphomaC8orf86 →+0.025+4.191<.001.00731
BLOOD_LymphomaOR2T7 →+0.078+4.350<.001.00531
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

UNC93A by LY6H expression — BLOOD_Lymphoma

Box plot of UNC93A in LY6H-low vs LY6H-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration