LY6G6F-LY6G6D

Across TCGA patient cohorts, LY6G6F-LY6G6D mutation is significantly associated with the RNA expression of many other genes, with 220 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LY6G6F-LY6G6D-associated genes across cancer lineages are RN7SL375P, IGHVII-15-1, and RNU6-1169P. Each is linked with LY6G6F-LY6G6D in more than 1 cancer types. Because this analysis shows association rather than direction, both LY6G6F-LY6G6D-to-partner and partner-to-LY6G6F-LY6G6D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL375P grouped by LY6G6F-LY6G6D-low versus LY6G6F-LY6G6D-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6G6F-LY6G6D→partner) and Y-score (partner→LY6G6F-LY6G6D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL375P →	+0.179	+4.705	<.001	.003	3	2
SKCM	IGHVII-15-1 →	+0.077	+4.025	<.001	.007	3	2
UCEC	RNU6-1169P →	+0.478	+3.717	<.001	.005	3	2
UCEC	TRAJ47 →	+0.925	+4.105	<.001	.001	3	2
SKCM	RPS3AP1 →	+0.046	+2.943	<.001	.009	3	2
HNSC	MRPS21P5 →	+0.147	+5.303	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 220 associations by consensus.

RN7SL375P by LY6G6F-LY6G6D expression — CESC

Explore this box plot interactively →