LY6G6F-LY6G6D

Across TCGA pan-cancer cohorts, LY6G6F-LY6G6D RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated LY6G6F-LY6G6D data layer compared with 3 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher LY6G6F-LY6G6D RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LY6G6F-LY6G6D expression acts as an unfavorable survival marker, although some lineages such as COAD and CHOL show a favorable association.

KICH, LGG, and KIRC are the cancer types where LY6G6F-LY6G6D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
LGG	OS	Median	All	0.290	0.555	<.001	50	view →
KIRC	DFS	Tertile	IV	0.180	0.535	.018	36	view →
ACC	DFS	Tertile	II,III,IV	0.123	0.603	.013	24	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	18	view →
MESO	OS	Tertile	IV	0.036	0.602	<.001	18	view →
SKCM	OS	Tertile	All	0.221	0.359	.004	18	view →
CESC	OS	Quartile	IV	0.157	0.579	<.001	12	view →
COAD	OS	Median	IV	0.789	0.504	.003	11	view →
CHOL	DFS	Median	IV	0.858	0.339	.017	9	view →
LUAD	DFS	Tertile	All	0.727	0.801	.033	9	view →
UVM	OS	Tertile	All	0.452	0.945	.003	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

LY6G6F-LY6G6D–KICH (DFS)

Open the KICH breakdown →