LY6G6F-LY6G6D

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LY6G6F-LY6G6D mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LY6G6F-LY6G6D-associated genes across cancer lineages are Preadipocytes, aDC, and Eosinophils. Each is linked with LY6G6F-LY6G6D in more than 1 cancer types. Because this analysis shows association rather than direction, both LY6G6F-LY6G6D-to-partner and partner-to-LY6G6F-LY6G6D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by LY6G6F-LY6G6D-low versus LY6G6F-LY6G6D-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6G6F-LY6G6D→partner) and Y-score (partner→LY6G6F-LY6G6D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPreadipocytes →+0.063+3.754<.001.00832
SKCMaDC →-0.120-2.453.010.02031
SKCMEosinophils →+0.064+2.123<.001.03031
BLCAPlasma cells →+0.036+3.154.015.02431
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Preadipocytes by LY6G6F-LY6G6D expression — COAD

Box plot of Preadipocytes in LY6G6F-LY6G6D-low vs LY6G6F-LY6G6D-high samples in COAD.

Explore this box plot interactively →

Exploration