LY6G5B

Across TCGA patient cohorts, LY6G5B mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LY6G5B-associated genes across cancer lineages are RNU6-271P, NDUFA3P3, and DUTP5. Each is linked with LY6G5B in more than 1 cancer types. Because this analysis shows association rather than direction, both LY6G5B-to-partner and partner-to-LY6G5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-271P grouped by LY6G5B-low versus LY6G5B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6G5B→partner) and Y-score (partner→LY6G5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-271P →	+0.685	+4.852	<.001	.006	3	1
UCEC	NDUFA3P3 →	+0.496	+5.003	<.001	.002	3	1
UCEC	DUTP5 →	+0.239	+4.349	.001	.007	3	1
UCEC	SFPQP1 →	+0.103	+4.326	<.001	.007	3	1
UCEC	SC4MOP →	+0.116	+5.453	<.001	.002	3	1
UCEC	MIR1972-2 →	+1.156	+4.349	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

RNU6-271P by LY6G5B expression — UCEC

Explore this box plot interactively →