LTB4R2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LTB4R2 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LTB4R2-associated genes across cancer lineages are RN7SL248P, NF1P6, and RPL23AP90. Each is linked with LTB4R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LTB4R2-to-partner and partner-to-LTB4R2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTB4R2→partner) and Y-score (partner→LTB4R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.151+4.722<.001<.00132
UCECNF1P6 →+0.236+3.454<.001<.00132
UCECRPL23AP90 →+0.461+3.004.001.00631
BLCAMIR6779 →+0.776+5.020<.001<.00131
UCECSMCP →+0.205+2.871<.001.00731
UCECMAGEB18 →+0.080+3.398.003.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

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