LTB4R

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LTB4R mutation is significantly associated with the RNA expression of many other genes, with 1,123 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LTB4R-associated genes across cancer lineages are MTATP6P30, KIR3DP1, and MORF4L1P6. Each is linked with LTB4R in more than 2 cancer types. Because this analysis shows association rather than direction, both LTB4R-to-partner and partner-to-LTB4R results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTB4R→partner) and Y-score (partner→LTB4R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCMTATP6P30 →+0.154+7.954<.001.00833
CESCKIR3DP1 →+0.212+6.837<.001<.00132
HNSCMORF4L1P6 →+0.129+7.954<.001.00832
UCECRNU6-508P →+0.241+2.868<.001.00932
UCECRNU6-376P →+0.210+2.868<.001.00932
UCECRN7SKP264 →+0.204+2.029<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,123 associations by consensus.

Exploration