LSM12

Across TCGA patient cohorts, LSM12 protein abundance is significantly associated with the RNA expression of many other genes, with 11,469 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LSM12-associated genes across cancer lineages are CSF3R, FCGR3B, and CEACAM3. Each is linked with LSM12 in more than 5 cancer types. Because this analysis shows association rather than direction, both LSM12-to-partner and partner-to-LSM12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LSM12 versus CSF3R in GBM, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM12→partner) and Y-score (partner→LSM12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CSF3R →	-0.942	-0.307	<.001	<.001	3	6
LSCC	FCGR3B →	-1.295	-0.231	<.001	<.001	3	6
LSCC	CEACAM3 →	-0.693	-0.252	<.001	<.001	3	6
UCEC	TUBG1 →	+0.538	+0.232	.004	.002	3	5
UCEC	VPS25 →	+0.744	+0.205	<.001	.001	3	5
LSCC	DCAF13 →	+0.600	+0.184	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,469 associations by consensus.

LSM12 vs CSF3R — GBM

Explore this scatter interactively →