LRRD1

Across TCGA patient cohorts, LRRD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,071 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LRRD1-associated GO terms across cancer lineages are miRNA processing, Regulation of double-strand break repair, and Obsolete histone modification. Each is linked with LRRD1 in more than 26 cancer types. Because this analysis shows association rather than direction, both LRRD1-to-partner and partner-to-LRRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, miRNA processing grouped by LRRD1-low versus LRRD1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRD1→partner) and Y-score (partner→LRRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	miRNA processing →	+0.068	+0.082	<.001	<.001	3	27
STAD	Regulation of double-strand break repair →	+0.064	+0.089	<.001	<.001	3	26
SCLC	Obsolete histone modification →	+0.077	+0.243	<.001	<.001	3	26
STAD	Mitochondrial cytochrome c oxidase assembly →	+0.061	+0.089	<.001	<.001	3	26
STAD	Maintenance of cell number →	+0.067	+0.091	<.001	<.001	3	26
STAD	Positive regulation of DNA metabolic process →	+0.066	+0.088	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,071 associations by consensus.

miRNA processing by LRRD1 expression — STAD

Explore this box plot interactively →