LRRD1

Across TCGA cell cohorts, LRRD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,914 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRD1-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of syncytium formation by plasma membrane fusion, and Heterochromatin organization. Each is linked with LRRD1 in more than 8 cancer types. Because this analysis shows association rather than direction, both LRRD1-to-partner and partner-to-LRRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by LRRD1-low versus LRRD1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRD1→partner) and Y-score (partner→LRRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Epigenetic regulation of gene expression →	+0.043	+0.073	.005	.008	3	9
PANCREAS	Regulation of syncytium formation by plasma membrane fusion →	+0.099	+0.042	<.001	.001	3	8
BLOOD_Leukemia	Heterochromatin organization →	+0.030	+0.045	.001	.002	3	8
STOMACH	Negative regulation of gene expression, epigenetic →	+0.049	+0.074	.005	.007	3	7
SOFT_TISSUE	Chromatin looping →	+0.111	+0.064	<.001	.003	3	7
SOFT_TISSUE	Spliceosomal complex assembly →	+0.091	+0.068	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,914 associations by consensus.

Epigenetic regulation of gene expression by LRRD1 expression — STOMACH

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