LRRC8C-DT

Across TCGA patient cohorts, LRRC8C-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 13,499 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC8C-DT-associated proteins across cancer lineages are NCOA7, QKI, and LPIN3_S411. Each is linked with LRRC8C-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both LRRC8C-DT-to-partner and partner-to-LRRC8C-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC8C-DT versus NCOA7 in GBM, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC8C-DT→partner) and Y-score (partner→LRRC8C-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCOA7 →	+0.238	+0.304	.006	.002	3	5
BRCA	QKI →	+0.215	+0.272	<.001	<.001	3	4
COAD	LPIN3_S411 →	-0.477	-0.195	<.001	<.001	3	4
PDAC	SP4_S46 →	+0.605	+0.289	<.001	<.001	3	4
GBM	FLNB →	-0.457	-0.478	.003	<.001	3	4
BRCA	NCOA7_S179 →	+0.383	+0.231	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,499 associations by consensus.

LRRC8C-DT vs NCOA7 — GBM

Explore this scatter interactively →