LRRC75A

Across TCGA patient cohorts, LRRC75A protein abundance is significantly associated with the RNA expression of many other genes, with 1,760 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LRRC75A-associated genes across cancer lineages are CELF5, SLC22A15, and TBKBP1. Each is linked with LRRC75A in more than 2 cancer types. Because this analysis shows association rather than direction, both LRRC75A-to-partner and partner-to-LRRC75A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC75A versus CELF5 in COAD, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC75A→partner) and Y-score (partner→LRRC75A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CELF5 →	-0.915	-0.602	.001	.003	3	2
COAD	SLC22A15 →	+1.144	+0.578	.004	.003	3	2
COAD	TBKBP1 →	-0.697	-0.537	.007	.005	3	2
UCEC	DENND4A →	-0.596	-0.379	.007	.001	3	2
UCEC	RPS10P3 →	-2.706	-0.533	.003	.004	3	2
BRCA	SLC14A1 →	+0.688	+1.549	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,760 associations by consensus.

LRRC75A vs CELF5 — COAD

Explore this scatter interactively →