LRRC75A

Across TCGA patient cohorts, LRRC75A protein abundance is significantly associated with the protein abundance of many other proteins, with 3,494 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC75A-associated proteins across cancer lineages are ATRIP_S239, AGAP1, and EPHB3. Each is linked with LRRC75A in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC75A-to-partner and partner-to-LRRC75A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC75A versus ATRIP_S239 in LUAD, with a Pearson correlation of -0.79.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC75A→partner) and Y-score (partner→LRRC75A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ATRIP_S239 →	-1.137	-0.804	.001	<.001	3	2
GBM	AGAP1 →	+0.345	+0.406	.003	.001	3	2
LUAD	EPHB3 →	+0.562	+0.548	<.001	.001	3	2
LSCC	WHAMM_S795 →	-1.132	-0.568	.002	.001	3	2
GBM	XRN1 →	-0.237	-0.345	<.001	.002	3	2
COAD	RELCH_T143 →	+0.597	+0.641	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,494 associations by consensus.

LRRC75A vs ATRIP_S239 — LUAD

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