LRRC75A

Across TCGA cell cohorts, LRRC75A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,889 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LRRC75A-associated GO terms across cancer lineages are Mitochondrial electron transport, cytochrome c to oxygen, Aerobic electron transport chain, and ATP synthesis coupled electron transport. Each is linked with LRRC75A in more than 10 cancer types. Because this analysis shows association rather than direction, both LRRC75A-to-partner and partner-to-LRRC75A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, cytochrome c to oxygen grouped by LRRC75A-low versus LRRC75A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC75A→partner) and Y-score (partner→LRRC75A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.095	+0.508	<.001	.002	1	11
OVARY	Aerobic electron transport chain →	+0.092	+0.599	<.001	.001	3	9
OVARY	ATP synthesis coupled electron transport →	+0.095	+0.732	.002	<.001	3	9
OVARY	Mitochondrial ATP synthesis coupled electron transport →	+0.095	+0.732	.002	<.001	3	9
OVARY	Oxidative phosphorylation →	+0.088	+0.761	.001	.001	3	9
LUNG_SCLC	Mitotic cytokinesis →	+0.081	+1.263	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,889 associations by consensus.

Mitochondrial electron transport, cytochrome c to oxygen by LRRC75A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →