Across TCGA patient cohorts, LRRC74B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,030 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LRRC74B-associated GO terms across cancer lineages are DNA-templated transcription elongation, Positive regulation of double-strand break repair via homologous recombination, and Positive regulation of plasma membrane bounded cell projection assembly. Each is linked with LRRC74B in more than 21 cancer types. Because this analysis shows association rather than direction, both LRRC74B-to-partner and partner-to-LRRC74B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC74B→partner) and Y-score (partner→LRRC74B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA-templated transcription elongation →	+0.078	+0.152	<.001	<.001	3	22
ESCA	Positive regulation of double-strand break repair via homologous recombination →	+0.077	+0.156	<.001	.001	3	22
STAD	Positive regulation of plasma membrane bounded cell projection assembly →	+0.060	+0.134	<.001	<.001	3	22
STAD	Positive regulation of double-strand break repair →	+0.065	+0.150	<.001	<.001	3	22
STAD	Regulation of microtubule-based process →	+0.052	+0.155	<.001	<.001	3	22
STAD	Positive regulation of DNA metabolic process →	+0.069	+0.156	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,030 associations by consensus.

Exploration

LRRC74B survival (RNA) · tumor vs normal (RNA) · all LRRC74B data types