LRRC57

Across TCGA patient cohorts, LRRC57 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,382 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRRC57-associated proteins across cancer lineages are DNAJC17, RTF1, and SDF2L1. Each is linked with LRRC57 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRC57-to-partner and partner-to-LRRC57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC57 versus DNAJC17 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC57→partner) and Y-score (partner→LRRC57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DNAJC17 →	+0.265	+0.278	<.001	<.001	3	6
LSCC	RTF1 →	+0.252	+0.393	<.001	<.001	3	5
BRCA	SDF2L1 →	-0.381	-0.383	<.001	<.001	2	6
GBM	THEMIS2 →	-0.397	-0.306	.004	.002	3	5
OV	UBR1 →	+0.220	+0.389	<.001	<.001	3	5
LUAD	SEC24A →	-0.273	-0.459	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,382 associations by consensus.

LRRC57 vs DNAJC17 — GBM

Explore this scatter interactively →