LRRC57

Across TCGA cell cohorts, LRRC57 protein abundance is significantly associated with the RNA expression of many other genes, with 2,152 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible LRRC57-associated genes across cancer lineages are IL6R, SLC17A9, and MFAP1. Each is linked with LRRC57 in more than 4 cancer types. Because this analysis shows association rather than direction, both LRRC57-to-partner and partner-to-LRRC57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC57 versus IL6R in URINARY_TRACT, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC57→partner) and Y-score (partner→LRRC57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IL6R →	-1.125	-1.151	.004	.004	3	4
BLOOD_Leukemia	SLC17A9 →	+2.314	+0.893	.005	<.001	3	4
OVARY	MFAP1 →	+0.716	+1.539	<.001	<.001	3	4
OVARY	CRKL →	+0.858	+1.247	<.001	<.001	3	4
LUNG_NSCLC_LUSC	FAM120B →	+0.882	+1.115	.006	.008	3	4
LUNG_NSCLC_LUSC	BICRAL →	+0.940	+1.283	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,152 associations by consensus.

LRRC57 vs IL6R — URINARY_TRACT

Explore this scatter interactively →