LRRC52

Across TCGA cell cohorts, LRRC52 RNA expression is significantly associated with the go_rna of many other GO terms, with 94 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LRRC52-associated GO terms across cancer lineages are Negative regulation of cytosolic calcium ion concentration, Trabecula formation, and Hydrogen sulfide metabolic process. Each is linked with LRRC52 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC52-to-partner and partner-to-LRRC52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cytosolic calcium ion concentration grouped by LRRC52-low versus LRRC52-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC52→partner) and Y-score (partner→LRRC52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of cytosolic calcium ion concentration →	-0.184	-0.028	.001	.003	3	2
BREAST	Trabecula formation →	-0.206	-0.028	.001	.003	3	2
BREAST	Hydrogen sulfide metabolic process →	-0.156	-0.028	<.001	.004	3	2
BREAST	Plasma membrane raft assembly →	-0.156	-0.023	.002	.009	3	2
SKIN	Regulation of hydrogen peroxide biosynthetic process →	+0.138	+0.040	<.001	.005	3	1
SKIN	Somatic recombination of immunoglobulin gene segments →	-0.052	-0.040	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

Negative regulation of cytosolic calcium ion concentration by LRRC52 expression — BREAST

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