LRRC43

Across TCGA cell cohorts, LRRC43 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,275 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible LRRC43-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Cytoplasmic translation. Each is linked with LRRC43 in more than 13 cancer types. Because this analysis shows association rather than direction, both LRRC43-to-partner and partner-to-LRRC43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by LRRC43-low versus LRRC43-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC43→partner) and Y-score (partner→LRRC43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of myoblast fusion →	+0.117	+0.935	.002	.004	3	14
STOMACH	Negative regulation of myoblast fusion →	+0.131	+1.089	.002	.001	3	13
STOMACH	Cytoplasmic translation →	+0.086	+1.030	.003	.002	3	13
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.127	+0.931	.003	.005	3	12
OVARY	Aerobic respiration →	+0.072	+0.462	<.001	<.001	3	11
STOMACH	Regulation of RNA splicing →	+0.086	+1.082	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,275 associations by consensus.

Regulation of myoblast fusion by LRRC43 expression — STOMACH

Explore this box plot interactively →