LRRC3B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LRRC3B protein abundance is significantly associated with the RNA expression of many other genes, with 867 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC3B-associated genes across cancer lineages are PRODH, C22orf31, and RASL10A. Each is linked with LRRC3B in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC3B-to-partner and partner-to-LRRC3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC3B versus PRODH in GBM, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC3B→partner) and Y-score (partner→LRRC3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPRODH →+0.802+0.304.002.00831
GBMC22orf31 →+0.384+0.298.001.00431
GBMRASL10A →+0.860+0.445<.001<.00131
GBMCHADL →+1.228+0.417<.001<.00131
GBMCPNE6 →+0.733+0.301.002.00731
GBMSGK2 →+0.603+0.322.002.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 867 associations by consensus.

LRRC3B vs PRODH — GBM

Per-sample scatter of LRRC3B vs PRODH in GBM (Pearson r = 0.32).

Explore this scatter interactively →

Exploration