LRRC24

Across TCGA patient cohorts, LRRC24 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC24-associated genes across cancer lineages are LILRP1, MIR373, and KRT17P4. Each is linked with LRRC24 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC24-to-partner and partner-to-LRRC24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRP1 grouped by LRRC24-low versus LRRC24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC24→partner) and Y-score (partner→LRRC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LILRP1 →	+0.155	+3.547	.001	.007	3	1
UCEC	MIR373 →	+0.334	+4.132	.001	.009	3	1
UCEC	KRT17P4 →	+0.062	+4.063	<.001	<.001	3	1
UCEC	SNORD116-16 →	+0.502	+3.018	.008	.009	3	1
UCEC	RNU6-12P →	+0.271	+3.884	.009	.003	3	1
UCEC	TRAJ40 →	+0.654	+3.156	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

LILRP1 by LRRC24 expression — UCEC

Explore this box plot interactively →