LRRC24

Across TCGA pan-cancer cohorts, LRRC24 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LRRC24’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LRRC24 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LRRC24 is over-expressed in tumor, although a few such as COAD and STAD show the opposite, repressed pattern.

BRCA, LIHC, and COAD are the cancer types where LRRC24 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LRRC24 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.030	<.001	6	view →
LIHC	Female	All	+0.023	<.001	3	view →
COAD	Female	IV	−0.050	.037	2	view →
STAD	Male	IV	−0.095	.024	1	view →
KIRC	Male	All	−0.012	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LRRC24–BRCA

Open the BRCA breakdown →