LRP8

Across TCGA patient cohorts, LRP8 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,310 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRP8-associated proteins across cancer lineages are RIF1_S782, NCAPD2, and SMC2. Each is linked with LRP8 in more than 8 cancer types. Because this analysis shows association rather than direction, both LRP8-to-partner and partner-to-LRP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRP8 versus RIF1_S782 in OV, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP8→partner) and Y-score (partner→LRP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RIF1_S782 →	+1.159	+2.124	.004	.002	2	9
CCRCC	NCAPD2 →	+0.651	+0.845	.009	.006	3	7
UCEC	SMC2 →	+0.756	+1.069	<.001	<.001	3	7
BRCA	SMC4 →	+0.609	+0.722	<.001	<.001	3	7
COAD	TIMELESS_S1173 →	+0.687	+0.696	<.001	<.001	3	7
HNSC	TOP2A_S1106 →	+0.871	+0.721	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,310 associations by consensus.

LRP8 vs RIF1_S782 — OV

Explore this scatter interactively →