LRP4

Across TCGA patient cohorts, LRP4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,231 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRP4-associated genes across cancer lineages are CORO1A, IL21R, and PIK3CG. Each is linked with LRP4 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRP4-to-partner and partner-to-LRP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRP4 versus CORO1A in LSCC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP4→partner) and Y-score (partner→LRP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CORO1A →	-0.606	-0.393	.002	.002	3	3
GBM	IL21R →	-0.726	-0.355	<.001	<.001	3	3
GBM	PIK3CG →	-0.601	-0.408	<.001	<.001	3	3
LUAD	CD80 →	-0.696	-1.634	.001	.001	3	3
GBM	BTBD3 →	+0.449	+0.355	<.001	<.001	3	3
LSCC	ITGB7 →	-0.495	-0.491	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,231 associations by consensus.

LRP4 vs CORO1A — LSCC

Explore this scatter interactively →