LRP11

Across TCGA cell cohorts, LRP11 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRP11-associated genes across cancer lineages are AIPL1, FAM9A, and SLC18A3. Each is linked with LRP11 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRP11-to-partner and partner-to-LRP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AIPL1 grouped by LRP11-low versus LRP11-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP11→partner) and Y-score (partner→LRP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AIPL1 →	+0.057	+4.152	<.001	.009	3	1
BLOOD_Leukemia	FAM9A →	+0.016	+4.539	<.001	.007	3	1
BLOOD_Leukemia	SLC18A3 →	+0.010	+4.276	<.001	.007	3	1
BLOOD_Leukemia	OR8D1 →	+0.121	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR2A12 →	+0.019	+4.969	<.001	.003	3	1
BLOOD_Leukemia	MUC22 →	+0.005	+5.569	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

AIPL1 by LRP11 expression — BLOOD_Leukemia

Explore this box plot interactively →