LRP11

Across TCGA pan-cancer cohorts, LRP11 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of LRP11’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LRP11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LRP11 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

COAD, HNSC, and BLCA are the cancer types where LRP11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LRP11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+1.148	<.001	12	view →
HNSC	Male	All	+0.831	<.001	10	view →
BLCA	All	IV	+1.851	<.001	9	view →
LIHC	Female	III,IV	+1.326	<.001	9	view →
LUAD	All	III,IV	+0.830	<.001	9	view →
BRCA	All	III,IV	+0.786	<.001	8	view →
STAD	All	II,III,IV	+1.060	<.001	7	view →
LUSC	All	All	+0.684	<.001	7	view →
KIRC	Male	II,III,IV	−0.632	<.001	7	view →
THCA	All	III,IV	+0.490	<.001	7	view →
CHOL	Male	All	+2.224	<.001	5	view →
READ	All	III,IV	+1.684	.014	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

LRP11–COAD

Open the COAD breakdown →