LPCAT4

Across TCGA cell cohorts, LPCAT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,480 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible LPCAT4-associated GO terms across cancer lineages are Regulation of translation at postsynapse, modulating synaptic transmission, mRNA splice site recognition, and Cytoplasmic microtubule organization. Each is linked with LPCAT4 in more than 11 cancer types. Because this analysis shows association rather than direction, both LPCAT4-to-partner and partner-to-LPCAT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translation at postsynapse, modulating synaptic transmission grouped by LPCAT4-low versus LPCAT4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LPCAT4→partner) and Y-score (partner→LPCAT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of translation at postsynapse, modulating synaptic transmission →	+0.108	+1.063	<.001	<.001	3	12
BLOOD_Lymphoma	mRNA splice site recognition →	+0.103	+0.870	<.001	<.001	3	10
BONE	Cytoplasmic microtubule organization →	+0.070	+0.993	<.001	<.001	3	9
BLOOD_Lymphoma	Cell motility involved in cerebral cortex radial glia guided migration →	+0.083	+0.685	.004	.008	3	9
URINARY_TRACT	Negative regulation of protein-containing complex assembly →	+0.071	+1.118	.003	.005	3	9
BONE	Actomyosin contractile ring organization →	+0.122	+0.652	.002	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,480 associations by consensus.

Regulation of translation at postsynapse, modulating synaptic transmission by LPCAT4 expression — BONE

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