LPCAT1

Across TCGA patient cohorts, LPCAT1 mutation is significantly associated with the RNA expression of many other genes, with 2,002 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LPCAT1-associated genes across cancer lineages are RNU6-835P, VN1R54P, and LINC02706. Each is linked with LPCAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LPCAT1-to-partner and partner-to-LPCAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-835P grouped by LPCAT1-low versus LPCAT1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPCAT1→partner) and Y-score (partner→LPCAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-835P →	+0.124	+3.973	<.001	.008	3	2
LUAD	VN1R54P →	+0.515	+4.055	<.001	.005	3	2
LUAD	LINC02706 →	+1.093	+4.730	<.001	.005	3	2
SKCM	MIR6871 →	+0.544	+2.839	<.001	.001	3	2
UCEC	CTSH →	-0.608	-1.367	.001	.008	3	2
UCEC	KCTD9 →	+0.600	+1.818	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,002 associations by consensus.

RNU6-835P by LPCAT1 expression — COAD

Explore this box plot interactively →