LNPK

Across TCGA patient cohorts, LNPK mutation is significantly associated with the RNA expression of many other genes, with 2,439 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LNPK-associated genes across cancer lineages are RN7SL371P, RNU6-752P, and RNA5SP411. Each is linked with LNPK in more than 2 cancer types. Because this analysis shows association rather than direction, both LNPK-to-partner and partner-to-LNPK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL371P grouped by LNPK-low versus LNPK-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LNPK→partner) and Y-score (partner→LNPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SL371P →	+0.149	+4.523	<.001	.001	3	3
BRCA	RNU6-752P →	+0.194	+5.548	.003	.001	3	2
UCEC	RNA5SP411 →	+1.140	+2.393	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.613	+1.867	<.001	.007	3	2
BRCA	TDGF1P2 →	+0.049	+5.365	.009	.002	3	2
BRCA	MTND1P18 →	+0.200	+3.722	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,439 associations by consensus.

RN7SL371P by LNPK expression — LUAD

Explore this box plot interactively →