LMO4

Across TCGA patient cohorts, LMO4 mutation is significantly associated with the RNA expression of many other genes, with 1,656 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMO4-associated genes across cancer lineages are RNU6-1222P, ELOCP31, and RN7SL248P. Each is linked with LMO4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LMO4-to-partner and partner-to-LMO4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1222P grouped by LMO4-low versus LMO4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMO4→partner) and Y-score (partner→LMO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1222P →	+0.696	+4.225	<.001	.007	3	2
COAD	ELOCP31 →	+0.600	+3.525	<.001	.007	3	2
UCEC	RN7SL248P →	+0.056	+3.059	<.001	.005	3	2
UCEC	BNIP3P41 →	+0.011	+4.156	<.001	.004	3	2
BLCA	RNU6-436P →	+0.401	+5.329	<.001	.006	3	2
BRCA	H2AB2 →	+0.062	+7.473	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,656 associations by consensus.

RNU6-1222P by LMO4 expression — COAD

Explore this box plot interactively →