LMO3

Across TCGA cell cohorts, LMO3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,463 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LMO3-associated GO terms across cancer lineages are Gamma-aminobutyric acid signaling pathway, Regulation of systemic arterial blood pressure mediated by a chemical signal, and Oxidative phosphorylation. Each is linked with LMO3 in more than 6 cancer types. Because this analysis shows association rather than direction, both LMO3-to-partner and partner-to-LMO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gamma-aminobutyric acid signaling pathway grouped by LMO3-low versus LMO3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LMO3→partner) and Y-score (partner→LMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Gamma-aminobutyric acid signaling pathway →	-0.275	-0.493	<.001	<.001	3	7
BONE	Regulation of systemic arterial blood pressure mediated by a chemical signal →	-0.213	-3.449	<.001	<.001	3	7
LUNG_SCLC	Oxidative phosphorylation →	+0.096	+2.723	<.001	<.001	3	7
OVARY	Regulation of cytoplasmic translation →	+0.108	+2.613	<.001	.002	3	6
BONE	B cell chemotaxis →	-1.353	-4.216	<.001	<.001	3	6
SOFT_TISSUE	Alternative mRNA splicing, via spliceosome →	+0.095	+1.171	<.001	.005	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,463 associations by consensus.

Gamma-aminobutyric acid signaling pathway by LMO3 expression — LIVER

Explore this box plot interactively →