LMO3

Across TCGA pan-cancer cohorts, LMO3 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of LMO3’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where LMO3 RNA is repressed in tumor relative to normal tissue. In most cancer types LMO3 is over-expressed in tumor, although a few such as BLCA and KICH show the opposite, repressed pattern.

BLCA, KICH, and KIRC are the cancer types where LMO3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LMO3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−3.861	<.001	11	view →
KICH	Female	II,III,IV	−2.270	<.001	11	view →
KIRC	Male	II,III,IV	−1.882	<.001	11	view →
KIRP	Female	All	−1.654	<.001	11	view →
COAD	Male	II,III,IV	−2.107	<.001	10	view →
LUSC	Male	II,III,IV	−3.744	<.001	8	view →
THCA	Female	All	+1.104	<.001	8	view →
HNSC	All	All	−0.314	<.001	8	view →
BRCA	All	All	−1.093	<.001	6	view →
LUAD	All	All	−0.715	.002	6	view →
READ	All	III,IV	−3.250	<.001	5	view →
UCEC	All	All	−1.393	.003	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

LMO3–BLCA

Open the BLCA breakdown →