LMO3

Across TCGA pan-cancer cohorts, LMO3 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated LMO3 data layer compared with 2 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LMO3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LMO3 expression acts as an unfavorable survival marker, although some lineages such as SCLC and LUAD show a favorable association.

UCEC, SCLC, and LUSC are the cancer types where LMO3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.555	0.737	<.001	124	view →
SCLC	OS	Tertile	III,IV	0.880	0.366	<.001	67	view →
LUSC	DFS	Quartile	II,III,IV	0.585	0.857	.001	40	view →
LIHC	DFS	Tertile	All	0.454	0.618	<.001	37	view →
LUAD	OS	Quartile	All	0.869	0.725	<.001	32	view →
HNSC	OS	Quartile	III,IV	0.180	0.453	.004	27	view →
LAML	DFS	Median	All	0.589	0.338	.012	24	view →
KICH	DFS	Median	III,IV	0.341	0.891	.006	23	view →
KIRC	OS	Quartile	All	0.756	0.877	<.001	22	view →
KIRP	DFS	Quartile	All	0.528	0.761	.001	21	view →
BLCA	OS	Tertile	IV	0.155	0.455	.007	20	view →
CHOL	OS	Median	All	0.892	0.178	.002	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

LMO3–UCEC (DFS)

Open the UCEC breakdown →