LMO1

Across TCGA patient cohorts, LMO1 mutation is significantly associated with the RNA expression of many other genes, with 1,684 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMO1-associated genes across cancer lineages are ANOS2P, MIR103A1, and RN7SL314P. Each is linked with LMO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LMO1-to-partner and partner-to-LMO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANOS2P grouped by LMO1-low versus LMO1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMO1→partner) and Y-score (partner→LMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	ANOS2P →	+0.022	+5.539	<.001	.004	3	2
COAD	MIR103A1 →	+0.650	+5.136	<.001	.002	3	2
COAD	RN7SL314P →	+0.542	+5.020	<.001	<.001	3	2
UCEC	RN7SL248P →	+0.066	+3.307	<.001	.003	3	2
UCEC	ADIRF →	+0.018	+4.390	<.001	.003	3	2
LUSC	TRAJ21 →	+0.821	+4.312	.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,684 associations by consensus.

ANOS2P by LMO1 expression — CESC

Explore this box plot interactively →