LMO1

Across TCGA pan-cancer cohorts, LMO1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of LMO1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LMO1 RNA is repressed in tumor relative to normal tissue. In most cancer types LMO1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and UCEC are the cancer types where LMO1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LMO1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−2.127	<.001	11	view →
KIRC	Male	All	−0.804	<.001	8	view →
UCEC	All	All	+0.617	.017	8	view →
BLCA	Male	IV	−1.702	.002	6	view →
COAD	All	All	−0.164	<.001	6	view →
LUSC	Male	All	+0.693	<.001	5	view →
KIRP	Male	All	−1.256	<.001	4	view →
STAD	All	All	−1.037	.004	4	view →
LUAD	All	All	+0.226	.003	4	view →
THCA	Male	All	−0.193	.003	3	view →
ESCA	All	II,III,IV	−0.210	.042	2	view →
BRCA	Female	All	+0.157	.048	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

LMO1–KICH

Open the KICH breakdown →