LMNTD2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LMNTD2 mutation is significantly associated with the RNA expression of many other genes, with 2,691 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMNTD2-associated genes across cancer lineages are RNU6-142P, RNU6-3P, and RNU6-855P. Each is linked with LMNTD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LMNTD2-to-partner and partner-to-LMNTD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMNTD2→partner) and Y-score (partner→LMNTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-142P →+1.128+5.132<.001<.00133
COADRNU6-3P →+1.304+3.495<.001.00233
COADRNU6-855P →+1.010+4.278<.001.00133
COADRNU2-37P →+0.790+3.364<.001.00333
COADRN7SL570P →+0.588+4.821<.001.00333
COADMTCO1P55 →+0.474+3.067<.001.00833
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,691 associations by consensus.

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