Q-omics provides the consensus-scored MTCO1P55 profile across patient tissues and cancer cell-line models. MTCO1P55 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in TGCT. Among the 18 cancer types available for tumor–normal comparison, MTCO1P55 is differentially expressed in 3, with the highest sampling consensus in KIRP. Additionally, MTCO1P55 RNA expression shows 7,328 significant protein co-abundance associations, with the highest sampling consensus in PDAC. Together, these results highlight TGCT, KIRP, and PDAC as cancer lineages where MTCO1P55 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTCO1P55 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTCO1P55 survival associations across molecular data types. MTCO1P55 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTCO1P55 RNA expression–survival associations across cancer types. High MTCO1P55 expression shows unfavorable associations in TGCT, BRCA, CHOL, THYM and DLBC, but favorable associations in ESCA. The TGCT Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .006). Together, the overview and detailed table identify TGCT as the clearest survival context for MTCO1P55 RNA expression.
This table summarizes MTCO1P55 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for MTCO1P55. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTCO1P55 shows higher tumor expression in KIRP, KICH and KIRC. The KIRP box plot shows higher MTCO1P55 RNA expression in tumor versus normal tissue (log2 FC = +0.043, t-test p = .024).
This table shows molecular features associated with MTCO1P55 in patient tissues and cancer cell lines. In patient samples, MTCO1P55 shows the broadest associations at the RNA and protein expression levels, with PDAC recurring as the lineage with the largest associated feature set.
