MTCO1P55

Across TCGA pan-cancer cohorts, MTCO1P55 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MTCO1P55 data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher MTCO1P55 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTCO1P55 expression acts as an unfavorable survival marker, although some lineages such as ESCA and KIRP show a favorable association.

TGCT, CHOL, and BRCA are the cancer types where MTCO1P55 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	DFS	Tertile	II,III,IV	0.523	0.952	.006	54	view →
CHOL	DFS	Tertile	II,III,IV	0.116	0.420	.025	36	view →
BRCA	OS	Tertile	IV	0.275	0.857	.003	36	view →
THYM	OS	Tertile	II,III,IV	0.511	0.891	<.001	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
ESCA	OS	Tertile	All	0.658	0.429	.015	32	view →
UCEC	OS	Tertile	All	0.312	0.717	.004	30	view →
KIRP	OS	Tertile	All	1.000	0.671	.021	15	view →
LUSC	DFS	Tertile	All	0.888	0.725	.010	15	view →
STAD	DFS	Tertile	III,IV	0.603	0.409	.015	9	view →
PCPG	DFS	Tertile	All	0.848	0.940	.038	6	view →
LAML	DFS	Tertile	All	0.505	0.353	.046	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MTCO1P55–TGCT (DFS)

Open the TGCT breakdown →