LMNB1

Across TCGA patient cohorts, LMNB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 26,073 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LMNB1-associated proteins across cancer lineages are TOP2A_S1106, TOP2A_S1247, and POLD1. Each is linked with LMNB1 in more than 9 cancer types. Because this analysis shows association rather than direction, both LMNB1-to-partner and partner-to-LMNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LMNB1 versus TOP2A_S1106 in LUAD, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LMNB1→partner) and Y-score (partner→LMNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TOP2A_S1106 →	+1.301	+0.971	<.001	<.001	3	10
LUAD	TOP2A_S1247 →	+1.521	+0.942	<.001	<.001	3	10
GBM	POLD1 →	+0.395	+1.057	<.001	<.001	3	10
LUAD	PRC1_T481 →	+1.508	+0.841	<.001	<.001	3	10
OV	UNG_T60 →	+1.019	+1.282	<.001	<.001	3	10
LUAD	MCM2 →	+0.833	+1.009	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,073 associations by consensus.

LMNB1 vs TOP2A_S1106 — LUAD

Explore this scatter interactively →