LMNB1-DT

Across TCGA patient cohorts, LMNB1-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,030 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LMNB1-DT-associated GO terms across cancer lineages are Positive regulation of DNA-templated DNA replication, Positive regulation of DNA metabolic process, and Cell cycle DNA replication. Each is linked with LMNB1-DT in more than 24 cancer types. Because this analysis shows association rather than direction, both LMNB1-DT-to-partner and partner-to-LMNB1-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA-templated DNA replication grouped by LMNB1-DT-low versus LMNB1-DT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LMNB1-DT→partner) and Y-score (partner→LMNB1-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA-templated DNA replication →	+0.068	+0.242	<.001	<.001	3	25
STAD	Positive regulation of DNA metabolic process →	+0.069	+0.334	<.001	<.001	3	25
STAD	Cell cycle DNA replication →	+0.071	+0.230	<.001	<.001	3	24
STAD	Cell cycle G2/M phase transition →	+0.069	+0.307	<.001	<.001	3	24
STAD	Negative regulation of mitotic cell cycle phase transition →	+0.073	+0.320	<.001	<.001	3	24
STAD	Mitotic sister chromatid segregation →	+0.078	+0.273	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,030 associations by consensus.

Positive regulation of DNA-templated DNA replication by LMNB1-DT expression — STAD

Explore this box plot interactively →