LMAN1L

Across TCGA patient cohorts, LMAN1L mutation is significantly associated with the RNA expression of many other genes, with 2,102 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMAN1L-associated genes across cancer lineages are MMEL1-AS1, MIR190B, and LINC02425. Each is linked with LMAN1L in more than 2 cancer types. Because this analysis shows association rather than direction, both LMAN1L-to-partner and partner-to-LMAN1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMEL1-AS1 grouped by LMAN1L-low versus LMAN1L-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMAN1L→partner) and Y-score (partner→LMAN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MMEL1-AS1 →	+1.335	+6.147	<.001	.002	3	3
LIHC	MIR190B →	+0.214	+4.423	<.001	.007	3	2
HNSC	LINC02425 →	+0.121	+6.468	<.001	.001	3	2
COAD	RN7SL159P →	+0.109	+4.399	.001	.006	3	2
LUAD	KIF2B →	+0.015	+5.197	<.001	<.001	3	2
LUAD	KRTAP21-1 →	+0.104	+4.584	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,102 associations by consensus.

MMEL1-AS1 by LMAN1L expression — BLCA

Explore this box plot interactively →